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Intra-Cytoplasmic Sperm Injection (ICSI)

Intra-Cytoplasmic Sperm Injection (ICSI) is the process whereby a single sperm is injected directly into the cytoplasm of the egg. ICSI is the method of choice for patients with severe male factor infertility, and for patients who have had previously failed or poor fertilization resulting from conventional IVF.

Intra-Cytoplasmic Sperm Injection (ICSI) Information Packet

The eggs are retrieved from the woman's ovaries in the same way as for IVF.  The eggs are then stripped of all surrounding cells and placed in a droplet and the male partner's sperm placed in another droplet. The sperm can be obtained via ejaculation or in severe cases, directly from the testis or epididymis using microsurgical sperm retrieval techniques.

The oocyte is held in place by a specialized holding micropipette.  With a microinjection pipette, one sperm is picked up (aspirated) and then carefully injected into the cytoplasm of the oocyte.  This is done for all the eggs. The eggs are then placed in the incubator, and checked the next morning for fertilization.

The fertilized eggs are then allowed to develop for another 24-48hr, after which they are transferred into the uterus via a thin catheter. Hormonal treatment to help maintain a pregnancy is given for the next 2 weeks.

The success rate for ICSI is usually around 30-35%.

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About Purchasing Intra-Cytoplasmic Sperm Injection (ICSI) Information Packet

Each Intra-Cytoplasmic Sperm Injection (ICSI) Information Packet includes the following:

  • Detailed description of the procedure
  • List of things to do before the procedure
  • What to expect during the procedure
  • Instructions for care after the procedure
  • Questions to ask your doctor